Progressive Supranuclear Palsy - PSP

Progressive Supranuclear Palsy (PSP)

On October 19-20, 2023, a significant global event brought together leading specialists to address the pressing issues surrounding Progressive supranuclear palsy (PSP) in London, UK

Progressive supranuclear palsy (PSP) is a rare and complex neurodegenerative disorder.

Here are 10 important things to know about PSP:

  1. Rare Condition: PSP is a relatively uncommon condition, affecting approximately 5-6 people per 100,000 in the population.
  2. Onset and Age: It typically affects individuals in their 60s or 70s, but early-onset PSP can occur in individuals in their 40s or 50s.
  3. Motor Symptoms: PSP is characterized by motor difficulties, including stiffness, slowness of movement, and frequent falls. This can make it resemble Parkinson’s disease, but PSP has distinct features.
  4. Eye Movement Problems: One of the hallmark features of PSP is difficulty controlling eye movements, leading to issues with looking up and down. This can cause falls and difficulty with balance.
  5. Cognitive Changes: Individuals with PSP may experience cognitive changes, such as difficulties with memory, decision-making, and problem-solving. However, these changes are usually less severe than those seen in Alzheimer’s disease.
  6. Behavioral and Emotional Changes: PSP can lead to changes in behavior and emotions, including irritability, apathy, and mood swings.
  7. Speech and Swallowing Issues: Speech problems, such as slurred speech, and difficulties with swallowing are common in PSP.
  8. No Cure: Currently, there is no cure for PSP. Treatment primarily focuses on managing symptoms and improving the patient’s quality of life.
  9. Abnormal Brain Protein: PSP is associated with the buildup of an abnormal protein called tau in specific areas of the brain. This protein accumulation is a key feature in diagnosing the condition.
  10. Diagnosis Challenges: Diagnosing PSP can be challenging because its symptoms overlap with other neurological disorders, like Parkinson’s disease. A definitive diagnosis often requires a combination of clinical evaluation, medical history, and specific neurological tests.

Supportive Care: PSP patients benefit from a multidisciplinary approach involving neurologists, physical therapists, occupational therapists, and speech therapists. Supportive care and therapy focus on symptom management and maintaining the patient’s quality of life. CurePSP and PSPA (Progressive Supranuclear Palsy Association) are two organizations dedicated to supporting individuals and families affected by Progressive supranuclear palsy (PSP) and related disorders

It’s important to note that PSP is a progressive and challenging condition that can significantly impact a person’s quality of life. Raising awareness and understanding of the disease is crucial for providing better care and support for individuals living with PSP and their families.

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